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Hui-Min Chung
Assistant Professor
Ph.D., Columbia University, Dept. Genetics and Development
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Email: hchung@uwf.edu
Phone: 850-474-2321
Courses Taught
Genetics, Genetic Engineering, Molecular Genetics, Human Genetics
Research Interests
I am interested in understanding how an animal develops. My laboratory utilizes the powerful genetics of the common fruit fly Drosophila melanogaster to study signaling transductions that regulate cell fate determination and cell growth. I am also a strong advocate of enrooting undergraduate science education in doing basic research. Students in my lab participate various research activities including developmental genetics and genomic studies.
Current Research
My recent focus has been to investigate how Presenilin, a protein which is a very important player in animal development and in causing human diseases like Alzheimer’s disease, networks with other proteins to deliver its functioning. We have established an animal system that enables us to study Presenilin function at any developmental stage. Our recent finding indicates that Presenilin not only is important to induce signal transduction that favors cell differentiation and growth, but might also be capable to suppress cell proliferation. We hope further studies on how Presenilin networks with other proteins will illustrate the detailed mechanisms of the diverse roles of Presenilin in animal development.
Selected Publication
- Barakat, A., Mercier, B., Cooper, E., and Chung, H.-M., (2009) Examining requirement for formation of functional Presenilin proteins and their processing events in vivo Genesis 47(3): 161-8.
- Cooper, E., Deng, W.-M., and Chung, H.-M. (2009) Aph-1 is required to regulate Presenilin-mediated gamma-secretase activity and cell survival in Drosophila wing development Genesis. 47(3): 169-74.
- David Lopatto, Consuelo Alvarez, Daron Barnard, Chitra Chandrasekaran, Hui-Min Chung, Chunguang Du, Todd Eckdahl, Anya Goodman, Charles Hauser, Christopher Jones, Olga Kopp, Gary Kuleck, Gerard McNeil, Robert Morris, Jennifer Myka, Alexis Nagengast, Paul Overvoorde, Jeffrey Poet, Kelynne Reed, Gloria Regisford, Dennis Revie, Anne Rosenwald, Kenneth Saville, Mary Shaw, Elizabeth Shoop, Gary Skuse, Christopher Smith, Mary Smith, Mary Spratt, Joyce Stamm, Jeffrey Thompson, Colette Witkowski, James Youngblom, Wilson Leung, Christopher Shaffer, Jeremy Buhler, Elaine Mardis, Sarah C R Elgin (2008) UNDERGRADUATE RESEARCH: Genomics Education Partnership Science 322. 684 - 685
